suppl fig 2 final

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4000. 5000. 6000. 7000. 8000. Primary cultures. Supplementary Figure 2. 0. 50. 100. 150. 200. 250. 300. 350. 400. 450. 500. Primary cultures. Microcephalin. A.
A ASPM 8000 7000 6000 5000 4000 3000 2000 Normalised gene expression 1000 0 P6 P7

T8 T9 T10T14T15T18T20T22T25T26T27 A56A60A82A89A90A92A95A96A98 A111 A110 A114 A117 A118 A119 A100 A101 A102 A103 A106 A109 A120 A126 A127 A128 A129 A130 A131 A135 A136 A141 A150 A168 A172 A174 A175 A178 Primary cultures

microcephalin

B

Microcephalin 500 450 400 350 300 250 200 150 100 Normalised gene expression 50 0 P6 P7

T8 T9 T10T14T15T18T20T22T25T26T27 A56A60A82A89A90A92A95A96A98 A111 A110 A114 A117 A118 A119 A100 A101 A102 A103 A106 A109 A120 A126 A127 A128 A129 A130 A131 A135 A136 A141 A150 A168 A172 A174 A175 A178 Primary cultures

Supplementary Figure 2