Supplementary Information for

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lymphopoiesis. Malay Mandal1*, Mark Maienschein-Cline2, Patrick Maffucci3, Margaret Veselits1, Domenick E. Kennedy1, Kaitlin C McLean1, Michael K ...
Supplementary Information for BRWD1 orchestrates epigenetic landscape of late B lymphopoiesis Malay Mandal1*, Mark Maienschein-Cline2, Patrick Maffucci3, Margaret Veselits1, Domenick E Kennedy1, Kaitlin C McLean1, Michael K Okoreeh1, Sophiya Karki3, Charlotte CunninghamRundles4, Marcus R Clark1*

1

Department of Medicine, Section of Rheumatology and Gwen Knapp Center for Lupus and

Immunology Research, University of Chicago, Chicago, Illinois, USA. 2

Core for Research Informatics, University of Illinois at Chicago, Chicago, Illinois, USA.

3

Department of Research Biology, Genentech, South San Francisco, California, USA

4

Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Division

of Clinical Immunology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

1

Supplementary Figure 1 BRWD1 enhances differentiation, and represses proliferation, transcription programs. a, b Ontology analysis (DAVID bioinformatics database) of gene clusters with lower (left panel, green) or higher (right panel, red) transcript abundance in Brwd1-/small pre-B cells than in WT small pre-B cells. Only terms with FDR