Supplementary Materials: Diagnosis by Volatile Organic ... - MDPI

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Volatile Organic Compounds in Exhaled Breath from Lung Cancer Patients Using Support Vector. Machine Algorithm. Yuichi Sakumura, Yutaro Koyama, HiroakiĀ ...
Sensors 2017, 17, doi:10.3390/s17020287; 287

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Supplementary Materials: Diagnosis by Volatile Organic Compounds in Exhaled Breath from Lung Cancer Patients Using Support Vector Machine Algorithm Yuichi Sakumura, Yutaro Koyama, Hiroaki Tokutake, Toyoaki Hida, Kazuo Sato, Toshio Itoh, Takafumi Akamatsu and Woosuck Shin Butane

0.6

0.3 0.2

0.25

0.25

Probability

Probability

Probability

0.4

0.2 0.15 0.1

0.1 0.2

0.4

0.6

0.8

0

1

0

50

100

ppb)

C8H16

0.05 5

0.3 0.2

0

10

0

0.1

0.2

20

0.3 0.2

0.3 0.2

0

0.6

0.2 0.15 0.1 0.05

0

0.5

1

1.5

ppb)

2

2.5

0

0

2

4

ppb)

(g)

8

(i)

Unknown

0.5

0.25

6

ppb)

(h)

Nonanal

80

0.25

0.1 0.4

60

Toluene

0.3

Probability

0.4

0.2

40

(f)

0.4

Probability

Probability

0

ppb)

Methylcyclohexane

0.5

0.1

0.4

Probability

Probability

0

0.3

(e)

0.5

0.2 0.15 0.1

0.3 0.2 0.1

0.05 0

0.1

ppb)

(d)

0.3

0.2 0.15

0.05

ppb)

Xylene

6

0.25

0.1

0

4

C8H17OH

0.3

Probability

Probability

Probability

0.1

0.6

2

(c)

0.4

0

0

ppb)

Dichlorobenzene

0.5

0.15

0

0

150

(b)

0.2

0

0.1

ppb)

(a) 0.25

0.2 0.15

0.05

0.05 0

2-Propanol

0.3

0.3

0.5

0

Acetone

0.35

0

1

2

3

0

0

5

10

ppb)

(j)

15

ppb)

(k)

Figure S1. VOC concentration distributions from lung cancer (red, n = 107) and healthy (green, n = 29) controlsā€™ breath; (a) butane; (b) acetone; (c) 2-propanol; (d) C8H16; (e) dichlorobenzene; (f) C8H17OH; (g) xylene; (h) methylcyclohexane; (i) tolunene; (j) nonanal; and (k) unknown compound.