systolic heart failure prediction of cardiac events in

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Nov 11, 2009 - A temporal difference between the septal to lateral wall (TsÀl) of $65 ms was defined as a mechanical dyssynchrony. Results After 33 months of ...
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Electrical and mechanical dyssynchrony for prediction of cardiac events in patients with systolic heart failure Goo-Yeong Cho, Hyung-Kwan Kim, Yong-Jin Kim, et al. Heart 2010 96: 1029-1032 originally published online November 11, 2009

doi: 10.1136/hrt.2009.167585

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Heart failure

Electrical and mechanical dyssynchrony for prediction of cardiac events in patients with systolic heart failure Goo-Yeong Cho,1 Hyung-Kwan Kim,2 Yong-Jin Kim,2 Dong-Ju Choi,1 Dae-Won Sohn,2 Byung-Hee Oh,2 Young-Bae Park2 1

Division of Cardiology, Seoul National University Bundang Hospital, Seoul National University, Seoul, South Korea 2 Division of Cardiology, Seoul National University Hospital, Seoul National University, Seoul, South Korea Correspondence to Professor Goo-Yeong Cho, Division of Cardiology, College of Medicine, Seoul National University and Cardiovascular Centre, Seoul National University Bundang Hospital, 300 Gumi-dong, Bundang-gu, Seongnam-si, Gyeonggi-do, 463-707, South Korea; [email protected] Accepted 20 October 2009 Published Online First 11 November 2009

ABSTRACT Background Recent clinical trials have challenged the clinical applicability of mechanical dyssynchrony in predicting cardiac resynchronisation therapy response. Objective To evaluate whether mechanical dyssynchrony has an additional benefit over QRS duration in predicting cardiac events in patients with systolic heart failure. Methods A total 167 patients admitted to hospital with heart failure (age 65 6 12, ejection fraction