Results were stratified by maternal pre-pregnancy BMI, classified according to WHO ... performed to estimate the association between maternal pre-preg-.
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[1.52,2.48]), 4.3(OR:1.97[1.49,2.60]) and 6.1(OR:2.04[1.50,2.78]). The rates of neonatal deaths among normal weight women were 4.3, 4.9, and 5.6 per 1,000 births respectively. In comparison the rates among obese women were 4.7(OR:1.13[.95,1.33]), 5.3(OR:1.12 [.89,1.39]), and 6.6(OR:1.22[.95,1.58]) respectively. The rates of NICU admission and low APGAR score were also significantly higher among obese pregnancies compared to normal weight controls (table 1). A dose-dependent relationship between maternal obesity and stillbirths was seen, but not for other neonatal outcomes (figure 2). CONCLUSION: Among neonates with birth weight below the 10th, 5th and 3rd percentile, maternal pre-pregnancy obesity were associated with increased risks for stillbirth, NICU admission and low APGAR scores but not neonatal death.
Table 1: SGA perinatal risks associated with maternal obesity Stillbirth
Neonatal Death NICU Admission Low APGAR
SGA Normal Weight 1.4/1,000 births 4.3/1,000 births
427 The effects of maternal obesity on fetal and neonatal outcomes among those born small for gestational age 1
2
Ruofan Yao , Bo Y. Park , Aaron B. Caughey
3
1.30%
2.9/1,000 births 4.7/1,000 births
9.90%
1.90%
Odds Ratio
1.94
1.13
1.15
1.29
95% CI
1.52, 2.48
.95, 1.33
1.10, 1.20
1.18, 1.41
SGA Normal Weight 2.1/1,000 births 4.9/1,000-births
1
University of Maryland Medical Center, Baltimore, MD, 2Johns Hopkins University, School of Public Health, Baltimore, MD, 3Oregon Health & Science University, Portland, OR
OBJECTIVE: Maternal obesity has been associated with higher birth
weight. Therefore we theorize that small for gestational age (SGA) neonates born to obese women are more likely to have associated pathological growth and increased neonatal complications compared to their counterparts born to normal weight women. STUDY DESIGN: This was a retrospective cohort study of all nonanomalous singleton neonates born in Texas from 2006-2011. Analysis was limited to births between 34 and 42 weeks gestation with birth weight below the 10th percentile among this cohort. Results were stratified by maternal pre-pregnancy BMI, classified according to WHO guideline. Neonatal and fetal outcomes of interest included stillbirth, neonatal death, neonatal intensive care unit(NICU) admission and 5 minute APGAR scores
