Page 1 ... Page 2. Adenosin triphosphate (ATP). N. N. NH2. -O. O. N. N. N. O. OH.
HO. O. P. O. O. O ... If volume is not changed: equal to change in inner energy ...
The role of ATP in metabolism
MUDr. Martin Vejražka, PhD. This slideshow is available onon-line
www.lf1.cuni.cz, link „e„e-learning“ el.lf1.cuni.cz
Adenosin triphosphate (ATP) NH 2
-O
O
N
N
P -
O
O -O
P
O
O
O O
N
N
O
P O-
HO
OH
ATP, ADP, AMP a cAMP Macroergic compound Role in signaling
– cAMP – AMP
Binds transitive metals RNA
What is macroergic bond??? … back to thermodynamics
Thermodynamics Two axioms Abstract quantities (entropy, enthalpy…) Idealised processes and stuffs (reversible action, universal gas…) Is not interested in inner structure of materia Does not deal with time, rate of processes
„Simple“ and „easy to understand“ system
Thermodynamic functions U H S F G
inner energy enthalpy = heat content entropy = measure of randomness free energy free enthalpy
Cannot be measured absolutely, changes are quantified Standard quantities (G0, S0…) defined for certain „standard state“
