Page 1 of 47 Articles in PresS. Am J Physiol Heart Circ Physiol (March 31, 2006). doi:10.1152/ajpheart.01362.2005
Ultrafine particulate matter exposure augments ischemia reperfusion injury in mice Emily Cozzi1, Surovi Hazarika1, Howard W. Stallings, III1,Wayne E. Cascio2, Robert B. Devlin3, Robert M. Lust1, Christopher J. Wingard1and Michael R. Van Scott1 Departments of 1Physiology and 2Internal Medicine Cardiology Division, Brody School of Medicine at East Carolina University, Greenville, NC 27834 and 3National Health and Environmental Effects Research Laboratory, EPA, Research Triangle Park, NC 27711
Running Head: Ultrafine particulate matter in mice
Address Correspondence to: Michael R. Van Scott, Ph.D. Department of Physiology Brody School of Medicine, East Carolina University 6N98 Brody Building Greenville, NC 27834. Telephone: (252) 744-3654 Fax: (252) 744-3460 E-mail:
[email protected]
Copyright Information Copyright © 2006 by the American Physiological Society.
Page 2 of 47
1 Abstract: Epidemiological studies have linked ambient particulate matter (PM) levels to an increased incidence of adverse cardiovascular events. Yet little is definitively known about the mechanisms accounting for the cardiovascular events associated with PMexposure. The goal of this study was to determine the effects of ultrafine (
