www.jyoungpharm.in Vol 2, Issue 4, Oct-Dec, 2010
[ISSN : 0975-1483]
Journal of
Young Pharmacists
An Official Quarterly Publication of InPharm Association A Young Pharmacists Group of India [An Addendum to InPharm Communique]
Editorial • Uncovering Negative Results: Introducing an Open Access Journal “Journal of Pharmaceutical Negative Results” Pharmaceutics • Development of a Floating Dosage Form of Ranitidine Hydrochloride by Statistical Optimization Technique • Floating Drug Delivery of Nevirapine as a Gastroretentive System • Preparation and Evaluation of Nano-vesicles of Brimonidine Tartrate as an Ocular Drug Delivery System Pharmacognosy • Enhancement of the Norfloxacin Antibiotic Activity by Gaseous Contact with the Essential Oil of Croton zehntneri • Free Radical Scavenging and Analgesic Activities of Cucumis sativus L. Fruit Extract Pharmacology • Antiulcer and Anti-inflammatory Activity of Aerial Parts Enicostemma littorale Blume • In Vitro Effects of Albendazole on Raillietina echinobothrida, the Cestode of Chicken, Gallus domesticus • Modulation of the P-Glycoproein-Mediated Intestinal Secretion of Glibenclamide: In Vitro and In Vivo Assessments • Evaluation of the Hypoglycemic Activity of Cucumis metuliferus (Cucurbitaceae) Fruit Pulp Extract in Normoglycemic and AlloxanInduced Hyperglycemic Rats Pharm Chemistry • Comparative Molecular Similarity Indices Analysis of 1(Naphthylalky1)-1H–imidazole Analogs with Antiepileptic Activity • Synthesis, Characterization, and Biological Evaluation of certain 6methyl-2(3H)-benzo-1, 3-thiazolyl-1'-ethylidene-2-(o, p- Substituted Acetophenones) Hydrazine Analogs • Anti-tumor Activity of N4 [(E)-1-(2-hydroxyphenyl) Methylidene], N4-[(E)4 2-Phenylethylidene], N [(E,2E)-3-Phenyl-2-propenylidene], and 4 N [(E)ethylidene] Isonicotinohydrazide on K562 and Jurkat Cell Lines Quality Assurance • Global Medical Device Nomenclature: The Concept for Reducing Device-Related Medical Errors Pharm Analysis • A Simple RP-HPLC Method for Quantitation of Itopride HCl in Tablet Dosage Form • Visible Spectrophotometric Estimation of Diacerein in Bulk and Pharmaceutical Dosage Forms
A Young Pharmacists’ Group of India
www.inpharm.org
Empowering Young Pharmacists
Pharmacognosy
!"#!$%&%!'()*('"%(+),-).#$/!(0!'/1/)'/$(0$'/2/'3(13(4#5%)65( Contact with the Essential Oil of Croton zehntneri Coutinho HDM, Matias EFF, Santos KKA, Tintino SR, Souza CES, Guedes GMM, Santos FAD, Costa JGM1, Falcão-Silva VS2, Siqueira-Júnior JP2 Laboratory of Microbiology and Molecular Biology and 1Laboratory of Research in Natural Products, Center of Biological Sciences and Health, University of the Region of Cariri, Crato (CE), Brazil, 2 Laboratory of Genetics of Microrganisms, Department of Molecular Biology, Center of Exacts and Natural Sciences, Federal University of Paraíba, João Pessoa (PB) Address for correspondence: Dr. Henrique Douglas Melo Coutinho; E-mail:
[email protected]
ABSTRACT !"#$"#$%!&$'(#%$)*$%!&$+),-./%")*$)0$*)(1)2/3"*$/*%"4")%"3$/3%"5"%6$46$%!&$5)./%".&$3)+7)-*,#$)0$/*$&##&*%"/.$)".8$ We report the chemical composition and antibiotic modifying activity of the essential oil extracted from the leaves of Croton zehntneri Pax et Hoffm (variety estragole), using the minimal inhibitory dose method and gaseous contact. The leaves of Croton zehntneri Pax et Hoffm (Euphorbiaceae) were subjected to hydrodistillation, and the essential oil extracted was examined with respect to the chemical composition, by gas chromatography-mass !"#$%&'"$%()*+,-./01)234)$&)536575$&%()2#$585$()&9)"9:;)0';+0)*/0:'3+1:1*
